产品货号：
Z19586
中文名称：
Laminin gamma 2/LAMC2抗体
英文名称：
Anti-Laminin gamma 2/LAMC2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Laminin gamma 2/LAMC2 Antibody |
| 指标别名 | B2T;BM600;CSF;CSF 140kDa subunit;EBR2;EBR2A;Epiligrin subunit gamma;Kalinin subunit gamma;Ladsin 140kDa subunit;LAMB2T;LAMC2;Laminin 5 subunit gamma;Laminin B2t chain;Laminin subunit gamma 2;laminin;gamma 2;LAMNB2;Nicein subunit gamma |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ELISA |
| 基因名称 | LAMC2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human LAMC2 recombinant protein (Position:A18-S1162). |
| 实际分子量 | 131KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Laminin gamma2,Laminin subunit gamma-2,is a protein that in humans is encoded by the LAMC2 gene.Laminins,a family of extracellular matrix glycoproteins,are the major noncollagenous constituent of basement membranes.They have been implicated in a wide variety of biological processes including cell adhesion,differentiation,migration,signaling,neurite outgrowth and metastasis.Laminins are composed of 3 non identical chains:laminin alpha,beta and gamma(formerly A,B1,and B2,respectively) and they form a cruciform structure consisting of 3 short arms,each formed by a different chain,and a long arm composed of all 3 chains.Each laminin chain is a multidomain protein encoded by a distinct gene.Several isoforms of each chain have been described.Different alpha,beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery,i.e.alpha1beta1gamma1 heterotrimer is laminin 1.The biological functions of the different chains and trimer molecules are largely unknown,but some of the chains have been shown to differ with respect to their tissue distribution,presumably reflecting diverse functions in vivo.This gene encodes the gamma chain isoform laminin,gamma 2.The gamma 2 chain,formerly though to be a truncated version of beta chain(B2t),is highly homologous to the gamma 1 chain;however,it lacks domain VI,and domains V,IV and III are shorter.It is expressed in several fetal tissues but differently from gamma 1,and is specifically localized to epithelial cells in skin,lung and kidney.The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5(earlier known as kalinin),which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane.The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule,and mutations in this gene have been associated with junctional epidermolysis bullosa,a skin disease characterized. |
| Uniprot ID | Q13753 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | laminin subunit gamma 2 |
| 蛋白名全称 | Laminin subunit gamma-2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 ELISA 1:100～1000 |
相关搜索：Laminin gamma 2/LAMC2抗体，Laminin gamma 2抗体，LAMC2多抗，Anti-Laminin gamma 2/LAMC2 Antibody